Peer-reviewed articles and book chapters (* indicates corresponding author). Patent applications are listed separately below.
Dr. Brumer also coordinates and actively contributes to CAZypedia – The Encyclopedia of Carbohydrate-Active Enzymes (see also article in Glycobiology, DOI:10.1093/glycob/cwx089). In addition, work in the group has produced the MediaWiki software extension BiblioPlus.
2023
174. Mathieu, Y., Raji, O., Bellemare, A., Di Falco, M., Nguyen, T.T.M., Viborg, A.H., Tsang, A., Master, E.*, Brumer, H.* (2023) Functional characterization of fungal lytic polysaccharide monooxygenases for cellulose surface oxidation. Biotechnol. Biofuels 16, 132. DOI:10.1186/s13068-023-02383-3
173. Janeček, Š.*, Brumer, H., Henrissat, B. (2023) News, trends, and challenges in Carbohydrate-Active enZymes. Biologia, 78, 1739-1740. DOI:10.1007/s11756-023-01449-9 (Editorial)
172. Arnal, G., Attia, M.A., Asohan, J., Lei, Z., Golisch, B., Brumer, H.* (2023) A low-volume, parallel copper-bicinchoninic acid (BCA) assay for glycoside hydrolases, Chapter 1 in Protein-Carbohydrate Interactions: Methods and Protocols, Abbott, W. and Zandberg, W. (eds.), Methods in Molecular Biology, 2657, 3-10. DOI:10.1007/978-1-0716-3151-5_1
171. Behar, H., Mottiar, Y., Chandrasekhar, R., Grappadelli, A.C., Pauly, M., Samuels, A.L., Mansfield, S.D., Brumer, H.* (2023) Populus endo-glucanase 16 localizes to the cell walls of developing tissues. Plant Direct, 7, e482. DOI:10.1002/pld3.482
170. Koncitikova, R., Zuily, L., Lemarié, E., Ribeaucourt, D., Saker, S., Haon, M., Brumer, H., Guallar, V., Berrin, J.-G.*, Lafond, M.* (2023) Rational engineering of AA5_2 copper radical oxidases to probe the molecular determinants governing their substrate selectivity. FEBS J., 290, 2658-2672. DOI:10.1111/febs.16713
2022
169. Fong, J.K., Brumer, H.* (2022) Copper radical oxidases: galactose oxidase, glyoxal oxidase, and beyond! Essays Biochem., EBC20220124. DOI:10.1042/EBC20220124
168. Bissaro, B., Kodama, S., Nishiuchi, T., Díaz-Rovira, A.M., Hage, H., Ribeaucourt, D., Haon, M., Grisel, S., Simaan, A.J., Beisson, F., Forget, S.M., Brumer, H., Rosso, M.-N., Guallar, V., O’Connell, R., Lafond, M., Kubo, Y.*, Berrin, J.-G.* (2022) Tandem metalloenzymes gate plant cell entry by pathogenic fungi. Sci. Adv., 8, eade9982. DOI:10.1126/sciadv.ade9982 (pre-print DOI:10.21203/rs.3.rs-493001/v1)
167. Kaddouch, E., Cleveland, M.E., Navarro, D., Grisel, S., Haon, M., Brumer, H., Lafond, M., Berrin, J.-G.*, Bissaro, B.* (2022) A simple and direct ionic chromatography method to monitor galactose oxidase activity. RSC Advances, 12, 26042-26050. DOI:10.1039/D2RA04485D
166. Mathieu, Y., Cleveland, M.E., Brumer, H.* (2022) Active-site engineering switches carbohydrate regiospecificity in a fungal Copper Radical Oxidase. ACS Catalysis, 12, 10264-10275. DOI:10.1021/acscatal.2c01956
165. Li, J., Goddard-Borger, E.D., Raji, O., Saxena, H., Solhi, L., Mathieu, Y., Master, E.R., Wakarchuk, W.W., Brumer, H.* (2022) Chitin-active lytic polysaccharide monooxygenases are rare in Cellulomonas species. Appl. Environ. Microbiol., 88, e00968-22. DOI:10.1128/aem.00968-22
164. 376, 1187-1191. DOI:10.1126/science.abo2401
163. Brumer, H.* (2022) Sticking to starch. J. Biol. Chem., 298, 102049. DOI:10.1016/j.jbc.2022.102049 (Commentary)
162. Solhi, L., Li, J., Li, J., Heyns, N.M.I., Brumer, H.* (2022) Oxidative enzyme activation of cellulose substrates for surface modification. Green Chem., 24, 4026-4040. DOI:10.1039/D2GC00393G
161. Behar, H., Samuels, L., Brumer, H.* (2022) Physcomitrium (Physcomitrella) patens endo-glucanase 16 is involved in the cell wall development of young tissue. Physiol. Plant., 174, e13683. DOI:10.1111/ppl.13683
160. Ostrowski, M.P., Leanti La Rosa, S., Kunath, B.J., Robertson, A., Pereira, G., Hagen, L.H., Varghese, N.J., Qiu, L., Yao, T., Flint, G., Li, J., McDonald, S., Buttner, D., Pudlo, N.A., Schnizlein, M.K., Young, V.B., Brumer, H., Schmidt, T., Terrapon, N., Lombard, V., Henrissat, B., Hamaker, B., Eloe-Fadrosh, E.A., Tripathi, A., Pope, P.B.*, Martens, E.* (2022) Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota. Nature Microbiol., 7, 556-569. DOI:10.1038/s41564-022-01093-0
159. Grondin, J.M., Déjean, G., Van Petegem, F., Brumer, H.* (2022) Cell surface xyloglucan recognition and hydrolysis by the human gut commensal Bacteroides uniformis. Appl. Environ. Microbiol., 88, e01566-21. DOI:10.1128/AEM.01566-21
2021
158. Cleveland, M.E., Mathieu, Y., Ribeaucourt, D., Haon, M., Mulyk, P., Hein, J.E., Lafond, M., Berrin, J-.G., Brumer, H.* (2021) A survey of substrate specificity among Auxiliary Activity Family 5 copper radical oxidases. Cell. Mol. Life Sci., 78, 8187–8208. DOI:10.1007/s00018-021-03981-w
157. Golisch, B., Lei, Z., Tamura, K., Brumer, H.* (2021) Configured for the human gut microbiota: Molecular mechanisms of dietary beta‑glucan utilization. ACS Chem. Biol., 16, 2087–2102. DOI:10.1021/acschembio.1c00563
156. Behar, H., Tamura, K., Wagner, E.R., Cosgrove, D.J., Brumer, H.* (2021) Conservation of endo-glucanase 16 (EG16) activity across highly divergent plant lineages. Biochem. J., 478, 3063-3078. DOI:10.1042/BCJ20210341
155. Cleveland, M., Lafond, M., Xia, F.R., Chung, R., Mulyk, P., Hein, J.E., Brumer H.* (2021) Two Fusarium copper radical oxidases with high activity on aryl alcohols. Biotechnol. Biofuels, 14, 138. DOI:10.1186/s13068-021-01984-0
154. Barghahn, S., Arnal, G., Jain, N., Petutschnig, E.K., Brumer, H., Lipka, V.* (2021) Mixed Linkage beta-1,3/1,4-glucan oligosaccharides induce defense responses in Hordeum vulgare and Arabidopsis thaliana. Front. Plant Sci., 12, 682439. DOI:10.3389/fpls.2021.682439
153. Solhi, L., Sun, H.S., Daswani, S.H., Shojania, S., Springate, C.M.K., Brumer, H.* (2021) Controlled sulfation of mixed-linkage glucan by response surface methodology for the development of biologically applicable polysaccharides. Carbohydr. Polym., 269, 118275. DOI:10.1016/j.carbpol.2021.118275
152. Jain, N., Tamura, K., Dejean, G., Van Petegem, F., Brumer, H.* (2021) Orthogonal active-site labels for mixed-linkage endo-beta-glucanases. ACS Chem. Biol., 16, 1968–1984. DOI:10.1021/acschembio.1c00063
151. Higgins, M.A.*, Tegl, G., MacDonald, S.S., Arnal, G., Brumer, H., Withers, S.G., Ryan, K.S.* (2021) N-glycan degradation pathways in gut- and soil-dwelling Actinobacteria share common core genes. ACS Chem. Biol., 16, 701–711. DOI:10.1021/acschembio.0c00995
150. Ribeaucourt, D., Bissaro, B., Guallar, V., Yemloul, M., Haon, M., Grisel, S., Alphand, V., Brumer, H., Lambert, F., Berrin, J.-G.*, Lafond, M.* (2021) Comprehensive insights into the production of long chain aliphatic aldehydes using a copper-radical alcohol oxidase as a biocatalyst. ACS Sustainable Chem. Eng., 9, 4411–4421. DOI:10.1021/acssuschemeng.0c07406
149. Tamura, K., Dejean, G., Van Petegem, F., Brumer, H.* (2021) Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota. J. Biol. Chem., 296, 100415. DOI:10.1016/j.jbc.2021.100415 (Editors’ Pick article)
148. Li, J., Solhi, L., Goddard-Borger, E.D., Mathieu, Y., Wakarchuk, W.W., Withers, S.G., Brumer, H.* (2021) Four cellulose-active lytic polysaccharide monooxygenases from Cellulomonas species. Biotechnol. Biofuels, 14, 29. DOI:10.1186/s13068-020-01860-3
147. Attia, M.A., Brumer, H.* (2021) New family of Carbohydrate-Binding Modules defined by a galactosyl-binding protein module from a Cellvibrio japonicus endo-xyloglucanase. Appl. Environ. Microbiol., 87, e02634-20. DOI:10.1128/AEM.02634-20
146. Tamura, K., Brumer, H.* (2021) Glycan utilization systems in the human gut microbiota: A gold mine for structural discoveries. Curr. Opin. Struct. Biol., 68, 26-40. DOI:10.1016/j.sbi.2020.11.001
145. Briggs, J.A., Grondin, J.M., Brumer, H.* (2021) Communal Living: Glycan Utilization by the Human Gut Microbiota. Environ. Microbiol., 23, 15-35. DOI:10.1111/1462-2920.15317
2020
144. Solhi, L., Sun, H.S., Daswani, S.H., Springate, C.M.K., Brumer, H.* (2020) Controlled sulfation of poly(vinyl alcohol) for biological and technical applications using response surface methodology. Mol. Syst. Des. Eng., 5, 1671 – 1678. DOI:10.1039/D0ME00139B
143. Jiao, C., Sørensen, I., Sun, X., Sun, H., Behar, H., Alseekh, S., Philippe, G., Palacio Lopez, K., Sun, L., Reed, R., Jeon, S., Kiyonami, R., Zhang, S., Fernie, A. R., Brumer, H., Domozych, D. S.*, Fei, Z.*, Rose, J.K.C.* (2020) The Penium margaritaceum genome: Hallmarks of the origins of land plants. Cell, 181, 964-966. DOI:10.1016/j.cell.2020.04.019
142. Déjean, G., Tamura, K., Cabrera, A., Jain, N., Pudlo, N.A., Pereira, G., Viborg, A.H., Van Petegem, F., Martens, E.C., Brumer, H.* (2020) Synergy between cell surface glycosidases and glycan-binding proteins dictates the utilization of specific beta(1,3)-glucans by human gut Bacteroides. mBio, . DOI:10.1128/mBio.00095-20
141. Forget, S.M., Xia, R., Hein, J.E.,* Brumer, H.* (2020) Determination of biocatalytic parameters of a copper radical oxidase using real-time reaction progress monitoring. Org. Biomol. Chem., 18, 2076 – 2084. DOI:10.1039/C9OB02757B
140. Mathieu, Y., Offen, W.A., Forget, S.M., Ciano, L., Viborg, A.H., Blagova, E., Henrissat, B., Walton, P.H., Davies, G.J., Brumer, H.* (2020) Discovery of a fungal copper radical oxidase with high catalytic efficiency towards 5-hydroxymethylfurfural and benzyl alcohols for bioprocessing. ACS Catalysis, 10, 3042-3058. DOI:10.1021/acscatal.9b04727
2019
139. Viborg, A.H. Terrapon, N., Lombard, V., Michel, G., Czjzek, M., Henrissat, B.*, Brumer, H.* (2019) A subfamily roadmap of the evolutionarily diverse Glycoside Hydrolase Family 16 (GH16). J. Biol. Chem., 294, 15973-15986. DOI:10.1074/jbc.RA119.010619
138. Tamura, K., Foley, M.H., Gardill, B.R., Dejean, G., Schnizlein, M., Bahr, C.M.E., Creagh, A.L., van Petegem, F., Koropatkin, N.M.*, Brumer, H.* (2019) Surface glycan binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus. Cell. Mol. Life. Sci., 76, 4319–4340. DOI:10.1007/s00018-019-03115-3 | SharedIt: free access (read-only)
137. Déjean, G., Tauzin, A.S., Bennett, S.W., Creagh, A.L., Brumer, H.* (2019) Adaptation of Syntenic Xyloglucan Utilization Loci of Human Gut Bacteroidetes to Polysaccharide Side Chain Diversity. Appl. Environ. Microbiol., 85, e01491-19. DOI:10.1128/AEM.01491-19 (selected as a Spotlight Article and for the front cover image in this issue).
136. Arnal, G., Stogios, P.J., Asohan, J., Attia, M., Skarina, T., Viborg, A.H., Henrissat, B., Savchenko, A.,* Brumer, H.* (2019) Substrate specificity, regiospecificity, and processivity in glycoside hydrolase family 74. J. Biol. Chem., 294, 13233-13247. DOI:10.1074/jbc.RA119.009861 (selected for the Editors’ Pick article and front cover image in this issue; Author profile: Gregory Arnal, Author profile: Peter J. Stogios).
135. Mollerup, F., Aumala, V., Parikka, K., Mathieu, Y., Brumer, H., Tenkanen, M., Master, E.* (2019) A family AA5_2 carbohydrate oxidase from Penicillium rubens displays functional overlap across the AA5 family. PLoS One, 14, e0216546. DOI:10.1371/journal.pone.0216546
134. Foley, M.H., Dejean, G., Hemsworth, G.R., Davies, G.J., Brumer, H., Koropatkin, N.M.* (2019) A cell-surface GH9 endo-glucanase coordinates with surface glycan binding proteins to mediate xyloglucan uptake in the gut symbiont Bacteroides ovatus. J. Mol. Biol., 431, 981-995. DOI:10.1016/j.jmb.2019.01.008
133. McKee, L.S.,* Martínez-Abad, A., Ruthes, A.C., Vilaplana, F., Brumer, H. (2019) Focused metabolism of beta-glucans by the soil Bacteroidetes species Chitinophaga pinensis. Appl. Environ. Microbiol., 85, e02231-18. DOI:10.1128/AEM.02231-18
2018
132. Arnal, G., Stogios, P.J., Asohan, J., Skarina, T., Savchenko, A., Brumer, H.* (2018) Structural enzymology reveals the molecular basis of substrate regiospecificity and processivity of an exemplar bacterial glycoside hydrolase family 74 endo-xyloglucanase. Biochem. J., 475, 3963-3978. DOI:10.1042/BCJ20180763 (Cover image)
131. Arola, S., Ansari, M., Oksanen, A., Retulainen, E., Hatzikiriakos, S.G., Brumer, H.* (2018) The sol-gel transition of ultra-low solid content TEMPO-cellulose nanofibril/mixed-linkage beta-glucan bionanocomposite gels. Soft Matter, 14, 9393-9401. DOI:10.1039/C8SM01878B
130. Jain, N., Attia, M.A., Offen, W.A., Davies, G.J., Brumer, H.* (2018) Synthesis and application of a highly branched, mechanism-based 2-deoxy-2-fluorooligosaccharide inhibitor of endo-xyloglucanases. Org. Biomol. Chem., 16, 8732-8741. DOI:10.1039/c8ob02250j (correction in Org. Biomol. Chem., 17, 398 (2019). DOI:10.1039/c8ob90185f)
129. Behar, H., Graham, S.W., Brumer, H.* (2018) Comprehensive cross-genome survey and phylogeny of glycoside hydrolase family 16 members reveals the evolutionary origin of EG16 and XTH proteins in plant lineages. Plant J., 95, 1114-1128. DOI:10.1111/tpj.14004
128. Moroz, O.V., Jensen, P.F., McDonald, S.P., McGregor, N., Blagova, E., Comamala, G., Segura, D.R., Anderson, L., Vasu, S.M., Rao, V.P., Giger, L., Sørensen, T.H., Monrad, R.N., Svendsen, A., Nielsen, J.E., Henrissat, B., Davies, G.J., Brumer, H.*, Rand, K.D.*, Wilson, K.S.* (2018) Structural dynamics and catalytic properties of a multimodular xanthanase. ACS Catalysis, 8, 6021-6034. DOI:10.1021/acscatal.8b00666
127. Arnal, G., Cockburn, D.W., Brumer, H., Koropatkin, N.M.* (2018) Structural basis for the flexible recognition of alpha-glucan substrates by Bacteroides thetaiotaomicron SusG. Protein Sci., 27, 1093-1101. DOI:10.1002/pro.3410
126. Attia, M.A., Nelson, C.E., Offen, W.A., Jain, N., Davies, G.J., Gardner, J.G., Brumer, H.* (2018) In vitro and in vivo characterization of three Cellvibrio japonicus Glycoside Hydrolase Family 5 members reveals potent xyloglucan backbone-cleaving functions. Biotechnol. Biofuels, 11, 45. DOI:10.1186/s13068-018-1039-6
125. The CAZypedia Consortium (2017) Ten years of CAZypedia: A living encyclopedia of carbohydrate-active enzymes. Glycobiology, 28, 3-8. DOI:10.1093/glycob/cwx089
2017
124. Nelson, C.E., Attia, M.A., Rogowski, A., Morland, C., Brumer, H., Gardner, J.G.* (2017) Comprehensive functional characterization of the Glycoside Hydrolase Family 3 enzymes from Cellvibrio japonicus reveals unique metabolic roles in biomass saccharification. Environ. Microbiol., 19, 5025-5039. DOI:10.1111/1462-2920.13959
123. Tamura, K., Hemsworth, G.R., Déjean, G., Rogers, T.E., Pudlo, N.A., Urs, K., Jain, N., Davies, G.J., Martens, E.C., Brumer, H.* (2017) Molecular mechanism by which prominent human gut Bacteroidetes utilize mixed-linkage beta-glucans, major health-promoting cereal polysaccharides, Cell Reports, 21, 417-430. DOI:10.1016/j.celrep.2017.09.049
122. Grondin, J.M., Tamura, K., Déjean, G., Abbott, D.W.*, Brumer, H.* (2017) Polysaccharide Utilization Loci: Fuelling microbial communities. J. Bacteriol., 99, e00860-16. DOI:10.1128/JB.00860-16
121. McGregor, N., Arnal, G., Brumer, H.* (2017) Quantitative kinetic characterization of glycoside hydrolases using high-performance anion-exchange chromatography (HPAEC), Chapter 2 in Protein-Carbohydrate Interactions: Methods and Protocols, Abbott, D.W. and Lammerts van Bueren, A. (eds.), Methods in Molecular Biology, 1588, 15-25. DOI:10.1007/978-1-4939-6899-2_2
120. Arnal, G., Attia, M.A., Asohan, J., Brumer, H.* (2017) A low-volume, parallel copper-bicinchoninic acid (BCA) assay for glycoside hydrolases, Chapter 1 in Protein-Carbohydrate Interactions: Methods and Protocols, Abbott, D.W. and Lammerts van Bueren, A. (eds.), Methods in Molecular Biology, 1588, 3-14. DOI:10.1007/978-1-4939-6899-2_1
119. Fanuel, M., Garajova, S., Ropartz, D., McGregor, N., Brumer, H., Rogniaux, H.,* Berrin, J.G.* (2017) The Podospora anserina lytic polysaccharide monooxygenase PaLPMO9H catalyzes oxidative cleavage of diverse plant cell wall matrix glycans. Biotechnol Biofuels, 10, 63. DOI:10.1186/s13068-017-0749-5
118. McGregor, N., Yin, V., Tung, C.-C., van Petegem, F., Brumer, H.* (2017) Crystallographic insight into the evolutionary origins of xyloglucan endo-transglycosylases and endo-hydrolases. Plant J., 89, 651-670. DOI:10.1111/tpj.13421 (Featured Article, cover image: DOI:10.1111/tpj.13356)
115. Robb, M., Hobbs, J.K., Woodiga, S.A., Shapiro-Ward, S., Suits, M.D.L., McGregor, N., Brumer, H., Yesilkaya, H., King, S.J., Boraston, A.B.* (2017) Molecular characterization of N-glycan degradation and transport in Streptococcus pneumoniae and its contribution to virulence, PLoS Pathog., 13, e1006090. DOI:10.1371/journal.ppat.1006090
2016
114. Benselfelt, T., Cranston, E.D., Ondaral, S., Johansson, E., Brumer, H., Rutland, M.W., Wågberg, L.* (2016) Adsorption of xyloglucan onto cellulose surfaces of different morphologies: An entropy-driven process. Biomacromolecules, 17, 2801–2811. DOI:10.1021/acs.biomac.6b00561
113. Hemsworth, G.R., Thompson, A.J., Stepper, J., Sobala, Ł.F., Coyle, T., Larsbrink, J., Spadiut, O., Goddard-Borger, E.D., Stubbs, K.A., Brumer, H.*, Davies, G.J.* (2016) Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut. Open Biol., 6, Article number: 160142. DOI:10.1098/rsob.160142
112. Attia, M.A., Brumer, H.* (2016) Recent structural insights into the enzymology of the ubiquitous plant cell wall glycan xyloglucan. Curr. Opin. Struct. Biol., 40, 43-53. DOI:10.1016/j.sbi.2016.07.005
111. Attia, M., Stepper, J., Davies, G.J., Brumer, H.* (2016) Functional and structural characterization of a potent GH74 endo-xyloglucanase from the soil saprophyte Cellvibrio japonicus unravels the first step of xyloglucan degradation. FEBS J., 283, 1701-1719. DOI:10.1111/febs.13696
110. Tauzin, A.S., Kwiatkowski, K.J., Orlovsky, N.I., Smith, C.J., Creagh, A.L., Haynes, C.A., Wawrzak, Z., Brumer, H.*, Koropatkin, N.M.* (2016) Molecular dissection of xyloglucan recognition in a prominent human gut symbiont. mBio, 7, e02134-15. DOI:10.1128/mBio.02134-15
109. Derikvand, F., Yin, D.T., Barrett, R., Brumer, H.* (2016) Cellulose-based biosensors for esterase detection. Anal. Chem., 88, 2989–2993. DOI:10.1021/acs.analchem.5b04661
108. Hemsworth, G.R.,* Déjean, G., Davies, G.J., Brumer, H. (2016) Learning from microbial strategies for polysaccharide degradation. Biochem. Soc. Trans., 44, 94-108. DOI:10.1042/BST20150180
107. McGregor, N., Morar, M., Fenger, T.H., Stogios, P., Lenfant, N., Yin, V., Xu, X., Evdokimova, E., Cui, H., Henrissat, B., Savchenko, A.,* Brumer, H.*(2016) Structure-function analysis of a mixed-linkage beta-glucanase/xyloglucanase from key ruminal Bacteroidetes Prevotella bryantii B14. J. Biol. Chem., 291, 1175-1197. DOI:10.1074/jbc.M115.691659
2015
106. Yin, D.T., Urresti, S., Lafond, M., Johnston, E.M., Derikvand, F., Ciano, L., Berrin, J.G., Henrissat, B., Walton, P.H., Davies, G.J., Brumer, H.*(2015) Structure-function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family. Nat. Commun., 6,
Article number: 10197. DOI:10.1038/ncomms10197
105. Gerttula, S., Zinkgraf, M., Muday, G., Lewis, D., Ibatullin, F.M., Brumer, H., Hart, F., Mansfield, S.D., Filkov, V., Groover, A.* (2015) Transcriptional and hormonal regulation of gravitropism of woody stems in Populus. Plant Cell, 27, 2800–2813. DOI:10.1105/tpc.15.00531 (Selected for the issue cover image. Comment in DOI:10.1105/tpc.15.00824)
104. McKee, L.S., Brumer, H.* (2015) Growth of Chitinophaga pinensis on plant cell wall glycans and characterisation of a Glycoside Hydrolase Family 27 β-L-arabinopyranosidase implicated in arabinogalactan utilisation. PLoS ONE, 10(10), e0139932. DOI:10.1371/journal.pone.0139932
103. Coyle, T., Brumer, H., Stubbs, K.A.* (2015) An improved preparation of some aryl alpha-L-arabinofuranosides for use as chromogenic substrates for alpha-L-arabinofuranosidases. Can. J. Chem., 93, 1176-1180. DOI:10.1139/cjc-2015-0227
102. Fenger, T.H., Brumer, H.* (2015) Synthesis and analysis of specific covalent inhibitors of endo-xyloglucanases. ChemBioChem., 16, 575–583. DOI:10.1002/cbic.201402663
2014
101. Oksanen, A.,* Retulainen, E., Brumer, H. (2014) Bulky paper with good strength and smoothness? Certainly! Nord Pulp Pap. Res. J., 29, 725-731. DOI:10.3183/NPPRJ-2014-29-04-p725-731
100. Banasiak, A., Ibatullin, F.M., Brumer, H., Mellerowicz, E.J.* (2014) Glycoside hydrolase activities in cell walls of sclerenchyma cells in the inflorescence stems of Arabidopsis thaliana visualized in situ. Plants, 3, 513-525. DOI:10.3390/plants3040513
99. Larsbrink, J., Thompson, A.J., Lundqvist, M., Gardner, J.G., Davies, G.J., Brumer, H.* (2014) A complex gene locus enables xyloglucan utilization in the model saprophyte Cellvibrio japonicus. Mol. Microbiol., 94, 418–433. DOI:10.1111/mmi.12776
98. Brumer, H.,* Gilbert, H.* (2014) Editorial Overview: Carbohydrate-protein interactions: The future is taking shape. Curr. Opin. Struct. Biol., 28, v–vii. DOI:10.1016/j.sbi.2014.09.001
97. Martens, E.C.,* Kelly, A.G., Tauzin, A.S., Brumer, H.* (2014) The devil lies in the details: How variations in polysaccharide fine-structure impact the physiology and evolution of gut microbes. J. Mol. Biol., 426, 3851–3865. DOI:10.1016/j.jmb.2014.06.022
96. Anasontzis, G.E.,* Penã, M.S., Spadiut, O., Brumer, H., Olsson, L. (2014) Effects of temperature and glycerol- and methanol- feeding profiles on the production of recombinant galactose oxidase in Pichia pastoris. Biotechnol. Progress, 30, 728-735. DOI:10.1002/btpr.1878
95. Larsbrink, J., Rogers, T.E., Hemsworth, G.R., McKee, L.S., Tauzin, A.S., Spadiut, O., Klinter, S., Pudlo, N.A., Urs, K., Koropatkin, N.M., Creagh, A.L., Haynes, C.A., Kelly, A.G., Nilsson Cederholm, S., Davies, G.J.*, Martens, E.C.*, Brumer, H.* (2014) A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes. Nature, 506, 498–502. DOI:10.1038/nature12907 (Press releases: UBC, MSL, University of York, KTH; Spotlight: Trends Biochem. Sci.; Recommended: F1000Prime; Headline: UniProt release 2014_03)
94. Song, Y., Gyarmati, P., Araújo, A.C., Lundeberg, J., Brumer, H., Ståhl, P.L.* (2014) Visual Detection of DNA on Paper Chips. Anal. Chem., 86, 1575-1582. DOI:10.1021/ac403196b
93. Wang, Y., Vilaplana, F., Brumer, H., Aspeborg, H.* (2014) Enzymatic characterization of a glycoside hydrolase family 5 subfamily 7 (GH5_7) mannanase from Arabidopsis thaliana. Planta, 239, 653-665. DOI:10.1007/s00425-013-2005-y
92. Leppänen, A.-S.,* Xu, C., Parikka, K., Eklund, P., Sjöholm, R., Brumer, H., Tenkanen, M., Willför, S. (2014) Targeted allylation and propargylation of galactose-containing polysaccharides in water. Carbohydr. Polym., 100, 46-54. DOI:10.1016/j.carbpol.2012.11.053
2013
91. Eklöf, J.M., Shojania, S., Okon, M., McIntosh, L.P., Brumer, H.* (2013) Structure-function analysis of a broad-specificity Populus trichocarpa endo-beta-glucanase reveals an evolutionary link between bacterial licheninases and plant XTH gene products. J. Biol. Chem., 288, 15786-15799. DOI:10.1074/jbc.M113.462887
90. Thongpoo, P., McKee, L.S., Araújo, A.C., Kongsaeree, P.T., Brumer, H.* (2013) Identification of the acid/base catalyst of a glycoside hydrolase family 3 (GH3) beta-glucosidase from Aspergillus niger ASKU28. Biochim. Biophys. Acta – Gen. Subj., 1830, 2739–2749. DOI:10.1016/j.bbagen.2012.11.014
89. Stepper, J., Dabin, J., Eklöf, J.M., Thongpoo, P., Kongsaeree, P., Taylor, E., Turkenburg, J.P., Brumer, H., Davies, G.J.* (2013) Structure and Activity of the Streptococcus pyogenes family GH1 6-phospho beta-D-glycosidase, SPy1599. Acta Crystallogr. D Biol. Crystallogr., D69, 16-23. DOI:10.1107/S0907444912041005
88. Kaewthai, N., Gendre, D., Eklöf, J.M., Ibatullin, F.M., Ezcurra, I, Bhalerao, R.P., Brumer, H.* (2013) Group III-A XTH genes of Arabidopsis thalianaencode predominant xyloglucan endo-hydrolases that are dispensable for normal growth. Plant Physiol., 161, 440-454. DOI:10.1104/pp.112.207308
2012
87. Larsbrink, J., Izumi, A., Hemsworth, G.R., Davies, G.J.,* Brumer, H.* (2012) Structural enzymology of Cellvibrio japonicus Agd31B reveals α-transglucosylase activity in glycoside hydrolase family 31. J. Biol. Chem., 287, 43288–43299. DOI:10.1074/jbc.M112.416511
86. Aspeborg, H., Coutinho, P.M., Wang, Y., Brumer, H., Henrissat, B.* (2012) Evolution, substrate specificity and subfamily classification of glycoside hydrolase family 5 (GH5). BMC Evolutionary Biology,12, 186. DOI:10.1186/1471-2148-12-186
85. Parikka, K.,* Leppänen, A.S., Xu, C., Pitkänen, L., Eronen, P., Österberg, M., Brumer, H., Willför, S., Tenkanen, M. (2012) Functional and anionic cellulose-interacting polymers by selective chemo-enzymatic carboxylation of galactose-containing polysaccharides. Biomacromolecules, 13, 2418-2428. DOI:10.1021/bm300679a
84. Silipo, A.,* Larsbrink, L., Marchetti, R., Lanzetta, R., Brumer, H.,* Molinaro,A. (2012) NMR analysis reveals extensive binding interactions of complex xyloglucan oligosaccharides with the Cellvibrio japonicus Glycoside Hydrolase Family 31 alpha-xylosidase. Chemistry, 18, 13395–13404.DOI:10.1002/chem.201200488
83. Araújo, A.C., Nakhai, A., Ruda, M., Slättegård, R., Gatenholm, P., Brumer, H.* (2012) A general route to xyloglucan-peptide conjugates for the activation of cellulose surfaces. Carbohydr. Res., 354, 116-120. DOI:10.1016/j.carres.2012.03.038
82. Eklöf, J.M., Ruda, M., Brumer, H.* (2012) Distinguishing xyloglucanase activity in endo-beta(1-4)glucanases. Method. Enzymol., Vol. 510, Ch. 6, pp. 97-120. DOI:10.1016/B978-0-12-415931-0.00006-9
81. Araújo, A.C., Song, Y., Lundeberg, J., Ståhl, P.L., Brumer, H.* (2012) Activated paper surfaces for the rapid hybridization of DNA through capillary transport. Anal. Chem., 84, 3311–3317. DOI:10.1021/ac300025v (Correction in Anal. Chem., 2013, 85, 11676. DOI: 10.1021/ac403673s)
80. Bi, R., Spadiut, O., Lawoko, M., Brumer, H., Henriksson, G. (2012) Isolation and identification of microorganisms from soil able to live on lignin as a carbon source and to produce enzymes which cleave the beta-O-4 bond in a lignin model compound. Cellulose Chem. Technol., 46, 227-242. Online access: Article, Issue.
79. Xu, C., Spadiut, O., Araújo, A.C., Nakhai, A., Brumer, H.* (2012) Chemo-enzymatic assembly of clickable cellulose surfaces via multivalent polysaccharides. ChemSusChem, 5, 661–665. DOI:10.1002/cssc.201100522
2011
78. Zhang, Q., Brumer, H., Ågren, H., Tu, Y.* (2011) The adsorption of xyloglucan on cellulose: Effects of explicit water and side chain variation. Carbohydr. Res., 346, 2595-2602. DOI:10.1016/j.carres.2011.09.007
77. Ariza, A., Eklöf, J.M., Spadiut, O., Offen, W.A., Roberts, S.M., Besenmatter, W., Friis, E.P., Skjot, M., Wilson, K.S.*, Brumer, H.*, Davies, G.J.* (2011) Structure and activity of a Paenibacillus polymyxa xyloglucanase from glycoside hydrolase family 44. J. Biol. Chem., 286, 33890-33900. DOI:10.1074/jbc.M111.262345
76. Spadiut, O., Ibatullin, F.M., Peart, J., Gullfot, F., Martinez-Fleites, C., Ruda, M.C., Xu, C., Sundqvist, G., Davies, G.J., Brumer, H.* (2011) Building custom polysaccharides in vitro with an efficient, broad-specificity xyloglucan glycosynthase and a fucosyltransferase. J. Am. Chem. Soc., 133, 10892-10900. DOI:10.1021/ja202788q (Showcased in “The Chemistry-Glycobiology Frontier” issue of JACS Select)
75. Mark, P., Zhang, Q., Czjzek, M., Brumer, H., Ågren, H.* (2011) Molecular dynamics simulations of a branched tetradecasaccharide substrate in the active site of a xyloglucan endo-transglycosylase. Mol. Simulat., 37, 1001-1013. DOI:10.1080/08927022.2011.566605
74. Larsbrink, J., Izumi, A., Ibatullin, F.M., Nakhai, A., Gilbert, H.J., Davies, G.J., Brumer, H.* (2011) Structural and enzymatic characterisation of a Glycoside Hydrolase Family 31 alpha‑xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification. Biochem. J., 436, 567-580. DOI: 10.1042/BJ20110299
73. Oksanen, A.,* Rantanen, T., Retulainen, E., Salminen, K., Brumer, H. (2011) Improving Wet Web Runnability and Paper Quality by an Uncharged Polysaccharide. Journal of Biobased Materials and Bioenergy, 5, 187-191. DOI: 10.1166/jbmb.2011.1144
72. Cartmell, A., McKee, L., Pena, M.J., Larsbrink, J., Brumer, H., Kaneko, S., Ichinose, H., Lewis, R.J., Vikso-Nielsen, A., Gilbert, H.J.,* Marles-Wright, J. (2011) The structure and function of an arabinan-specific alpha-1,2-arabinofuranosidase identified from screening the activities of bacterial GH43 glycoside hydrolases. J. Biol. Chem., 286, 15483-15495. DOI: 10.1074/jbc.M110.215962
71. Fink, H., Ahrenstedt, L., Bodin, A., Brumer, H., Gatenholm, P., Krettek, A., Risberg, B. (2011) Bacterial cellulose modified with xyloglucan bearing the adhesion peptide RGD promotes endothelial cell adhesion and metabolism—a promising modification for vascular grafts. J. Tissue Eng. Regen. Med., 5, 454-463. DOI: 10.1002/term.334
70. Maris, A., Kaewthai, N., Eklöf, J.M., Miller, J.G., Brumer, H., Fry, S.C., Verbelen, J.-P., Vissenberg, K.* (2011) Differences in enzymic properties of five recombinant xyloglucan endotransglucosylase/hydrolase (XTH) proteins of Arabidopsis thaliana. J. Exp. Bot., 62, 261-271. DOI:10.1093/jxb/erq263.
69. Nishikubo, N., Takahashi, J., Roos, A.A., Derba-Maceluch, M., Piens, K., Brumer, H., Teeri, T.T., Stålbrand, H., and Mellerowicz, E.J.* (2011) Xyloglucan endo-transglycosylase-mediated xyloglucan rearrangements in developing wood of hybrid aspen (Populus tremula x tremuloides). Plant Physiol., 155, 399-413. DOI: 10.1104/pp.110.166934
2010
68. Lombard, V., Bernard, T., Rancurel, C., Brumer, H., Coutinho, P.M., and Henrissat, B.* (2010) A hierarchical classification of polysaccharide lyases for glycogenomics. Biochem. J., 432, 437–444. DOI: 10.1042/BJ20101185
67. Spadiut, O., Olsson, L., Brumer, H.* (2010) A comparative summary of expression systems for the recombinant production of galactose oxidase. Microb. Cell Fact., 9:68. DOI: 10.1186/1475-2859-9-68
66. Eklöf, J.M., Brumer, H.* (2010) The XTH gene family: An update on enzyme structure, function, and phylogeny in xyloglucan remodelling. Plant Physiol., 153, 456-466. DOI:10.1104/pp.110.156844.
65. Kaewthai, N., Harvey, A.J., Hrmova, M., Brumer, H.*, Ezcurra, I., Teeri, T.T., Fincher, G.B. (2010) Heterologous expression of diverse barley XTHgenes in the yeast Pichia pastoris. Plant Biotechnology, 27, 251-258. DOI: 10.5511/plantbiotechnology.27.251
64. Brumer, H. (2010) “Carbohydrases” in The Encyclopedia of Catalysis, 2nd Edition, István T. Horváth, ed., John Wiley and Sons, New York (Online 5 March). DOI: 10.1002/0471227617.eoc037
63. Brumer, H. (2010) “Enzymatic functionalization of cellulosic fibres: xyloglucan as a molecular anchor” in Advances in Textile Biotechnology, Vincent Nierstrasz & Artur Cavaco-Paulo, eds., Woodhead Publishing, Cambridge, pp. 266-287. ISBN-13: 978 1 84569 625 2. (Download uncorrected proof).
62. Guce, A.I., Clark, N.E., Salgado, E.N., Ivanen, D.R., Kulminskaya, A.A., Brumer, H., Garman, S.C.* (2010) The catalytic mechanism of human alpha-galactosidase. J. Biol. Chem., 285, 3625-3632. DOI: 10.1074/jbc.M109.060145
61. Gullfot, F., Tan, T.C., von Schantz, L., Nordberg Karlsson, E., Ohlin, M., Brumer, H., and Divne, C.* (2010) The crystal structure of XG-34, an evolved xyloglucan-specific carbohydrate-binding module. Proteins, 78, 785-789. DOI: 10.1002/prot.22642
2009
60. von Schantz, L., Gullfot, F., Scheer, S., Filonova, L., Cicortas Gunnarsson, L., Flint, J.E., Daniel, G., Nordberg-Karlsson, E., Brumer, H., and Ohlin, M.* (2009) Affinity maturation generates greatly improved xyloglucan-specific carbohydrate binding modules. BMC Biotechnol., 9, 92. DOI: 10.1186/1472-6750-9-92
59. Ibatullin, F.M., Banasiak, A., Baumann, M.J., Greffe, L., Takahashi, J., Mellerowicz, E.J. and Brumer, H.* (2009) A real-time fluorogenic assay for the visualization of glycoside hydrolase activity in planta. Plant Physiol., 151, 1741-1750. DOI: 10.1104/pp.109.147439
58. Zhou, Q.,* Brumer, H., and Teeri, T.T. (2009) Self-Organization of cellulose nanocrystals adsorbed with xyloglucan oligosaccharide-poly(ethylene glycol)-polystyrene triblock copolymer. Macromolecules, 42, 5430–5432. DOI: 10.1021/ma901175j
57. Gullfot, F., Ibatullin, F.M., Sundqvist, G., Davies, G.J., and Brumer, H.* (2009) Functional characterization of xyloglucan glycosynthases from GH7, GH12 and GH 16 scaffolds. Biomacromolecules, 10, 1782–1788. DOI: 10.1021/bm900215p
56. Takahashi, J., Rudsander, U.J., Hedenström, M., Banasiak, A., Harholt, J., Amelot, N., Immerzeel, P., Ryden, P., Endo, S., Ibatullin, F.M., Brumer, H., del Campillo, E., Master, E.R., Vibe Scheller, H., Sundberg, B., Teeri, T.T., and Mellerowicz, E.J.* (2009) KORRIGAN1 and its aspen homologue PttCel9A1 decrease cellulose crystallinity in Arabidopsis stem. Plant Cell Physiol., 50, 1099-1115. DOI: 10.1093/pcp/pcp062
55. Eklöf, J.M., Tan, T.C., Divne, C., and Brumer, H.* (2009) The crystal structure of the outer membrane lipoprotein YbhC from Escherichia coli sheds new light on the phylogeny of carbohydrate esterase family 8. Proteins, 76, 1029-1036. DOI: 10.1002/prot.22453
54. Eneyskaya, E.V., Sundqvist, G., Golubev, A.M., Ibatullin, F.M., Ivanen, D.R., Shabalin, K.A., Brumer, H., and Kulminskaya, A.A.* (2009) Transglycosylating and hydrolytic activities of the beta-mannosidase from Trichoderma reesei. Biochimie, 91, 632-638. DOI: 10.1016/j.biochi.2009.03.009
53. Mark, P., Baumann, M.J., Eklöf, J.M., Gullfot, F., Michel, G., Kallas, Å.M., Teeri, T.T., Brumer, H.,* and Czjzek, M.* (2009) Analysis of nasturtium TmNXG1 complexes by crystallography and molecular dynamics provides detailed insight into substrate recognition by family GH16 xyloglucan endo-transglycosylases and endo-hydrolases. Proteins, 75, 820-836 DOI: 10.1002/prot.22291
2008
52. Ibatullin, F.M., Baumann, M.J., Greffe, L., Brumer, H.* (2008) Kinetic analyses of retaining endo– (xylo)glucanases from plant and microbial sources using new chromogenic xylogluco-oligosaccharide aryl glycosides. Biochemistry, 47, 7762-7769. DOI: 10.1021/bi8009168
51. Piens, K., Faure, R., Sundqvist, G., Baumann, M.J., Saura-Valls, M., Teeri, T.T., Cottaz, S., Planas, A., Driguez, H., Brumer, H.* (2008) Mechanism-based labelling defines the free energy change for formation of the covalent glycosyl-enzyme intermediate in a xyloglucan endo-transglycosylase. J. Biol. Chem., 283, 21864-21872. DOI: 10.1074/jbc.M803057200
50. Saura-Valls, M., Faure, R., Brumer, H., Teeri, T.T., Cottaz, S., Driguez, H., Planas, A.* (2008) Active-site mapping of a populus xyloglucan endo-transglycosylase with a library of xylogluco-oligosaccharides. J. Biol. Chem., 283, 21853-21863. DOI: 10.1074/jbc.M803058200
49. Gilbert, H.J., Stålbrand, H., Brumer, H.* (2008) How the walls come crumbling down: Recent structural biochemistry of plant polysaccharide degradation. Curr. Opin. Plant Biol., 11, 338-348. DOI: 10.1016/j.pbi.2008.03.004
48. Rudsander, U.J., Sandstrom, C., Piens, K., Master, E.R., Wilson, D.B., Brumer, H., Kenne, L., Teeri, T.T.* (2008) Comparative NMR Analysis of Cellooligosaccharide Hydrolysis by GH9 Bacterial and Plant Endo-1,4-beta-glucanases. Biochemistry, 47, 5235-5241. DOI: 10.1021/bi702193e
47. Nordgren, N., Eklöf, J.M., Zhou, Q., Brumer, H., Rutland, M.W.* (2008) Top-down grafting of xyloglucan to gold monitored by QCM-D and AFM: Enzymatic activity and interactions with cellulose. Biomacromolecules, 9, 942–948. DOI: 10.1021/bm701214e
46. Ahrenstedt, L., Oksanen, A., Salminen, K., Brumer, H.* (2008). Paper dry strength improvement by xyloglucan addition: Wet-end application, spray coating, and synergism with borate. Holzforschung, 62, 8-14. DOI: 10.1515/HF.2008.002
2007
45. Bodin, A., Ahrenstedt, L., Fink, H., Brumer, H., Risberg, B., Gatenholm, P.* (2007). Modification of nanocellulose with a xyloglucan-RGD conjugate enhances adhesion and proliferation of endothelial cells: Implications for tissue engineering. Biomacromolecules, 8, 3697–3704. DOI: 10.1021/bm070343q
44. Piens, K., Henriksson, A.-M., Gullfot, F., Lopez, M., Fauré, R., Ibatullin, F.M., Teeri, T.T., Driguez, H., Brumer, H.* (2007). Glycosynthase activity of hybrid aspen xyloglucan endo-transglycosylase PttXET16-34 nucleophile mutants. Org. Biomol. Chem., 5, 3971-3978. DOI: 10.1039/b714570e
43. Baumann, M.J., Eklöf, J.M., Michel, G., Kallas, Å.M., Teeri, T.T., Czjzek, M.* and Brumer, H.* (2007). Structural evidence for the evolution of xyloglucanase activity from xyloglucan endo-transglycosylases: Biological implications for cell wall metabolism. Plant Cell, 19, 1947-1963. DOI: 10.1105/tpc.107.051391 (Recommended in Faculty of 1000 Prime)
42. Teeri, T.T.,* Brumer, H., Daniel, G. and Gatenholm, P. (2007). Biomimetic engineering of cellulose-based materials. Trends Biotech., 25, 299-306. DOI: 10.1016/j.tibtech.2007.05.002
41. Nishikubo, N., Awano, T., Banasiak, A., Bourquin, V., Ibatullin, F., Funada, R., Brumer, H., Teeri, T.T., Hayashi, T., Sundberg, B. and Mellerowicz, E.J.* (2007). Xyloglucan endo-transglycosylase (XET) functions in gelatinous layers of tension wood fibers in poplar – a glimpse into the mechanism of the balancing act of trees. Plant Cell Physiol., 48, 843-855. DOI: 10.1093/pcp/pcm055
40. Gloster, T.M., Ibatullin, F.M., Macauley, K., Eklöf, J.M., Roberts, S., Turkenburg, J.P., Bjørnvad, M.E., Linå Jørgensen, P., Danielsen, S., Johansen, K.S., Borchert, T.V., Wilson, K.S., Brumer, H.,* and Davies, G.J.* (2007). Characterisation and 3-D structures of two distinct bacterial xyloglucanases from families GH5 and GH12. J. Biol. Chem., 282, 19177-19189. DOI: 10.1074/jbc.M700224200
39. Zhou, Q., Rutland, M.W., Teeri, T.T., and Brumer, H.* (2007). Xyloglucan in cellulose modification. Cellulose, 14, 625-641. DOI: 10.1007/s10570-007-9109-0
38. Sundqvist, G., Stenvall, M., Berglund, H., Ottosson, J., and Brumer, H.* (2007). A general, robust method for the quality control of intact proteins using LC-ESI-MS. J. Chrom. B, 852, 188-194. DOI: 10.1016/j.jchromb.2007.01.011
37. Comfort, D.A., Bobrov, K.S., Ivanen, D.R., Shabalin, K.A., Harris, J.M., Kulminskaya, A.A., Brumer, H., Kelly, R.M.* (2007). Biochemical analysis of Thermotoga maritima GH36 alpha-galactosidase (TmGalA) confirms the mechanistic commonality of clan GH-D glycoside hydrolases. Biochemistry, 46, 3319-3330. DOI: 10.1021/bi061521n
2006
36. Neustroev, K.N., Golubev, A.M., Sinnott, M.L., Borriss, R., Krah, M., Brumer, H., Eneyskaya, E.V., Shishlyannikov, S., Shabalin, K.A., Peshechonov, V.T., Korolev, V.G., Kulminskaya, A.A.* (2006). Transferase and hydrolytic activities of the laminarinase from Rhodothermus marinus and its M133A, M133C, and M133W mutants. Glycoconj. J., 23, 501-511. DOI: 10.1007/s10719-006-6733-0
35. Stiernstedt, J., Nordgren, N., Wågberg, L., Brumer, H., Gray, D.G., and Rutland, M.W.* (2006). Friction and forces between cellulose model surfaces: a comparison. J. Coll. Int. Sci., 303, 117-123. DOI: 10.1016/j.jcis.2006.06.070
34. Cicortas Gunnarsson, L., Zhou, Q., Montanier, C., Nordberg Karlsson, E., Brumer, H., and Ohlin, M.* (2006). Engineered xyloglucan specificity in a carbohydrate-binding module. Glycobiology, 16, 1171-1180. DOI: 10.1093/glycob/cwl038 (Recommended in Faculty of 1000 Prime)
33. Lönnberg, H., Zhou, Q., Brumer, H., Teeri, T., Malmström, E., and Hult, A.* (2006). Grafting of Cellulose Fibers with Poly(epsilon-caprolactone) and Poly(L-lactic acid) via Ring-Opening Polymerization. Biomacromolecules, 7, 2178-2185. DOI: 10.1021/bm060178z
32. Stiernstedt, J., Brumer, H., Zhou, Q., Teeri, T.T. and Rutland M.W.* (2006). Friction between Cellulose Surfaces and Effect of Xyloglucan Adsorption. Biomacromolecules, 7, 2147-2153. DOI: 10.1021/bm060100i
31. Zhou, Q., Baumann, M.J., Piispanen, P.S., Teeri, T.T., and Brumer, H.* (2006). Xyloglucan and xyloglucan endo-transglycosylases (XET): Tools for ex vivo cellulose surface modification. Biocatal. Biotransform., 24, 107-120. DOI: 10.1080/10242420500538217
30. Zhou, Q., Baumann, M.J., Brumer, H.*, and Teeri, T.T. (2006). The influence of surface chemical composition on the adsorption of xyloglucan to chemical and mechanical pulps. Carbohydr. Polym., 63, 449-458. DOI: 10.1016/j.carbpol.2005.09.015
29. Faure, R., Saura-Valls, M., Brumer, H., Planas, A., Cottaz, S., and Driguez, H.* (2006). Synthesis of a Library of Xylogluco-Oligosaccharides for Active-Site Mapping of Xyloglucan endo-Transglycosylase. J. Org. Chem., 71, 5151-5161. DOI: 10.1021/jo0525682
28. Martinez-Fleites, C., Guerreiro, C.I., Baumann, M.J., Taylor, E.J., Prates, J.A., Ferreira, L.M., Fontes, C.M., Brumer, H., and Davies, G.J.* (2006). Crystal structures of Clostridium thermocellum xyloglucanase, XGH74A, reveal the structural basis for xyloglucan recognition and degradation. J. Biol. Chem., 281, 24922-24933. DOI: 10.1074/jbc.M603583200
27. Saura-Valls, M., Faure, R., Ragas, S., Piens, K., Brumer, H., Teeri, T.T., Cottaz, S., Driguez, H., and Planas, A.* (2006). Kinetic analysis using low-molecular mass xyloglucan oligosaccharides defines the catalytic mechanism of a Populus xyloglucan endotransglycosylase. Biochem. J., 395, 99-106. DOI: 10.1042/BJ20051396
2005
26. Uhlén, M.* et al. (2005). A human protein atlas for normal and cancer tissues based on antibody proteomics. Mol. Cell. Proteomics, 4, 1920-1932. DOI: 10.1074/mcp.M500279-MCP200
25. Kallas, Å.M., Piens, K., Denman, S., Henriksson, H., Fäldt, J., Johansson, P., Brumer, H., Teeri, T.T.* (2005). Enzymatic properties of native and deglycosylated hybrid aspen (Populus tremula x tremuloides) xyloglucan endotransglycosylase 16A expressed in Pichia pastoris. Biochem. J., 390, 105-113. DOI: 10.1042/BJ20041749
24. Ghebremichael, K.A., Gunaratna, K.R., Henriksson, H., Brumer, H., and Dalhammar, G.* (2005). A simple purification and activity assay of the coagulant protein from Moringa oleifera seed. Water Res., 39, 2338-2344. DOI: 10.1016/j.watres.2005.04.012
23. Engfeldt, T., Renberg, B., Brumer, H., Nygren, P.-Å., and Eriksson Karlström, A.* (2005). Chemical synthesis of triple-labelled three-helix bundle binding proteins for specific fluorescent detection of unlabelled protein. ChemBioChem, 6, 1043-1050. DOI: 10.1002/cbic.200400388
22. Zhou, Q., Greffe, L., Baumann, M.J., Malmström, E., Teeri, T.T.,and Brumer, H.* (2005). The use of xyloglucan as a molecular anchor for the elaboration of polymers from cellulose surfaces: a general route for the design of biocomposites. Macromolecules, 38, 3547-3549. DOI: 10.1021/ma047712k
21. Greffe L., Bessueille L., Bulone V., and Brumer H.* (2005). Synthesis, preliminary characterization, and application of novel surfactants from highly branched xyloglucan oligosaccharides. Glycobiology, 15, 437-445. DOI: 10.1093/glycob/cwi013
20. Gustavsson M.T., Persson P.V., Iversen T., Martinelle M., Hult K., Teeri T.T., and Brumer, H.* (2005). Modification of cellulose fiber surfaces by use of a lipase and a xyloglucan endotransglycosylase. Biomacromolecules, 6, 196-203. DOI: 10.1021/bm049588i
19. Eneyskaya, E.V., Ivanen, D.R., Shabalin, K.A., Kulminskaya, A.A., Backinowsky, L.V., Brumer, H., and Neustroev, K.N.* (2005). Chemo-enzymatic synthesis of 4-methylumbelliferyl beta (1-4)-D-xylooligosides: new substrates for beta-D-xylanase assays. Org. Biomol. Chem., 3, 146-151. DOI: 10.1039/b409583a
2004
18. Johansson, P., Brumer, H., Baumann, M. J., Kallas, A. M., Henriksson, H., Denman, S. E., Teeri, T. T. and Jones, T. A.* (2004). Crystal structures of a poplar xyloglucan endotransglycosylase reveal details of transglycosylation acceptor binding. Plant Cell, 16, 874-886. DOI: 10.1105/tpc.020065(Recommended in Faculty of 1000 Prime)
17. Eriksson, T., Stals, I., Collen, A., Tjerneld, F., Claeyssens, M., Stalbrand, H. and Brumer, H.* (2004). Heterogeneity of homologously expressed Hypocrea jecorina (Trichoderma reeseii) Cel7B catalytic module. Eur. J. Biochem., 271, 1266-1276. DOI: 10.1111/j.1432-1033.2004.04031.x
16. Brumer, H., Zhou, Q., Baumann, M. J., Carlsson, K. and Teeri, T. T.* (2004). Activation of crystalline cellulose surfaces through the chemoenzymatic modification of xyloglucan. J. Am. Chem. Soc., 126, 5715-5721. DOI: 10.1021/ja0316770
2003
15. Teeri, T. T. and Brumer, H.* (2003). Discovery, characterisation and applications of enzymes from the wood-forming tissues of poplar: Glycosyl transferases and xyloglucan endotransglycosylases. Biocatal. Biotransform., 21, 173-179. DOI: 10.1080/1024-2420310001618492
14. Henriksson, H., Denman, S., Campuzano, I., Master, E., Ademark, P., Teeri, T.T., and Brumer, H.* (2003). N-linked glycosylation of native and recombinant cauliflower xyloglucan endotransglycosylase 16A. Biochem. J., 375, 61-73. DOI: 10.1042/BJ20030485
13. Christiernin, M., Henriksson, G., Lindstrom, M.E., Brumer, H., Teeri, T.T., Lindstrom, T.*, and Laine, J.* (2003). The effects of xyloglucan on the properties of paper made from bleached kraft pulp. Nord. Pulp Paper Res. J., 18, 182-187. DOI: 10.3183/NPPRJ-2003-18-02-p182-187
12. Borriss, R., Krah, M., Brumer, H., Kerzhner, M.A., Ivanen, D.R., Eneyskaya, E.V., Elyakova, L.A., Shishlyannikov, S.M., Shabalin, K.A., and Neustroev, K.N.* (2003). Enzymatic synthesis of 4-methylumbelliferyl (1-3)-beta-D-glucooligosaccharides – new substrates for beta-1,3-1,4-D-glucanase. Carbohydrate Res., 338, 1455-67. DOI: 10.1016/S0008-6215(03)00199-X
11. Johansson, P., Denman, S., Brumer, H., Kallas, Å.M., Henriksson, H., Bergfors, T., Teeri, T.T., and Jones, T.A.* (2003). Crystallization and preliminary X-ray analysis of a xyloglucan endotransglycosylase from Populus tremula x tremuloides. Acta Crystallogr. Sect. D, 59, 535-537. DOI: 10.1107/S090744490202348X
10. Eneyskaya, E.V., Brumer, H., Backinowsky, L.V., Ivanen, D.R., Kulminskaya, A.A., Shabalin, K.A., and Neustroev, K.N.* (2003). Enzymatic synthesis of beta-xylanase substrates: transglycosylation reactions of the beta-xylosidase from Aspergillus sp. Carbohydrate Res., 338, 313-325. DOI: 10.1016/S0008-6215(02)00467-6
2002
9. Brumer, H., “Carbohydrases” in The Encyclopedia of Catalysis, István T. Horváth, ed., John Wiley and Sons, New York, 2002. DOI: 10.1002/0471227617.eoc037
8. Bourquin, V., Nishikubo, N., Abe, H., Brumer, H., Denman, S., Eklund, M., Christiernin, M., Teeri, T.T., Sundberg, B., and Mellerowicz, E.J.* (2002). Xyloglucan endotransglycosylases have a function during the formation of secondary cell walls of vascular tissues. Plant Cell, 14, 3073-3088. DOI: 10.1105/tpc.007773
2001
7. Brun, E., Brumer, H., MacKenzie, L.F., Withers, S.G.,* McIntosh, L.P. (2001). Letter to the Editor: Assignment of selectively C-13-labeled cellopentaose synthesized using an engineered glycosynthase. J. Biomol. NMR, 21, 67-68. DOI: 10.1023/A:1011927400439
6. Becker, D., Braet, C., Brumer, H., Claeyssens, M., Divne, C., Fagerstrom, B.R., Harris, M., Jones, T.A., Kleywegt, G.J., Koivula, A., Mahdi, S., Piens, K., Sinnott, M.L.,* Stahlberg, J., Teeri, T.T., Underwood, M., Wohlfahrt, G. (2001). Engineering of a glycosidase Family 7 cellobiohydrolase to more alkaline pH optimum: the pH behaviour of Trichoderma reesei CeI7A and its E223S/A224H/L225V/T226A/D262G mutant. Biochem. J., 356, 19-30. biochemj.org/bj/356/bj3560019.htm
2000
5. Hart, D.O., He, S., Chany II, C.J., Withers, S.G., Sims, P.F.G., Sinnott, M.L., and Brumer, H.* (2000). Identification of Asp-130 as the catalytic nucleophile in the main alpha-galactosidase from Phanerochaete chrysosporium, a family 27 glycosyl hydrolase. Biochemistry, 39, 9826-9836. DOI: 10.1021/bi0008074
1999
4. Brumer, H., Sims, P.F.G., and Sinnott, M.L.* (1999). Lignocellulose degradation by Phanerochaete chrysosporium: purification and characterisation of the main alpha-galactosidase. Biochem. J., 339, 43-53. biochemj.org/bj/339/bj3390043.htm
1995
3. Moriarty, R.M.* and Brumer, H. (1995). Toward a general synthesis of A-ring trihydroxylated vitamin D analogs: synthesis of an A-ring synthon of ED-71 from D-arabinose. Tetrahedron Lett., 36, 9265-9268. DOI: 10.1016/0040-4039(95)02008-D
2. Moriarty, R.M.,* Booth, D.T., and Brumer, H. (1995). Palladium catalyzed alkylative cyclization of iodonium salts with enynes: a mild and stereoselective reaction using hypervalent iodine. Abstracts of Papers of the Amer. Chem. Soc., 210, 397.
1. Moriarty, R.M.,* Kim, J., and Brumer, H. (1995). A general synthetic route to A-ring hydroxylated vitamin D analogs from pentoses. Tetrahedron Lett., 36, 51-54. DOI: 10.1016/0040-4039(94)02209-T
Patents
This section includes patent applications and granted patents.
6. Ståhl, P., Brumer, H., Song, Y., de Araújo Silva, A.C., Lundeberg, J. (2011) Surface-functionalized cellulosic fibres, method of manufacture thereof and uses thereof. WO2013072408.
5. Slättegård, R., Ruda, M., Brumer, H. (2009) Aminated hemicellulose molecule and method for production thereof. WO2010090591
4. Bodin, A., Gatenholm, P., Fink, H., Risberg, B., Brumer, H., Ahrenstedt, N.L. (2008) Implantable material for medical or surgical applications. WO2008104528.
3. Zhou, Q., Brumer, H., Teeri, T.T., Stolt, J.P., Ödberg, L.G. (2007) Copolymer, modified polymer carbohydrate material, modified build polymer, composite material, and methods of preparation WO2007149045.
2. Brumer, H., Rutland, M.W., Sinnott, M.L., Teeri, T.T., Zhou, Q. (2006). Cross-linking involving a polymeric carbohydrate material. WO2006079512
1. Teeri, T.T. and Brumer, H. (2003). Enzymatic method for the modification of polymeric carbohydrate materials. WO 03/033813